Summary: When conversing, humans instantaneously predict meaning from fragmentary and ambiguous mspeech, long before utterance completion.They do this by integrating priors (initial assumptions about the world) with contextual evidence to rapidly decide on the most likely meaning.One powerful prior is attentional preference for agents, which biases
Multi-objective Optimization Design of Wet Friction Clutches
The drag torque of the wet clutch affects opheliasmuse.com the efficiency of the transmission, and the engagement torque of the clutch affects the reliability of the transmission.However, reducing the drag torque and increasing the engagement torque are generally contradictory.This study takes the wet friction clutch as the research object, and tak
Spin Evolution of Neutron Stars
In this paper we review the basics of magneto-rotational properties of Jeans neutron stars focusing on spin-up/spin-down behavior at different evolutionary stages.The main goal is to provide equations for the spin frequency changes in various regimes (radio pulsar, propeller, accretor, etc.).Since presently the spin behavior of neutron stars at all
Ubiquitin proteomics identifies RNA polymerase I as a target of the Smc5/6 complex
Summary: Ubiquitination controls numerous cellular processes, and its deregulation is associated with many pathologies.The Nse1 subunit in the Smc5/6 complex contains a RING domain with ubiquitin E3 ligase activity and essential functions in genome integrity.However, Nse1-dependent ubiquitin targets remain elusive.Here, we use label-free quantitati
Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants
ABSTRACTTranslocon pores formed in ribavirin coupon the eukaryotic cell membrane by a type III secretion system facilitate the translocation of immune-modulatory effector proteins into the host cell interior.The YopB and YopD proteins produced and secreted by pathogenic Yersinia spp.harboring a virulence plasmid-encoded type III secretion system pe